This just in:

Amazing video of AuroVist™ in action-- In vivo MicroCT of mouse after AuroVist™ 15 injection Note very high contrast in blood and heart, with little accumulation in liver. AuroVist™ is a revolutionary tool in vascular visualization-- It gives up to 3 times the contrast of iodine, and without the vascular damage! Created during recent experiments right here at the Nanoprobes Labs. Click to Play

5nm Ni-NTA-NanogoldTM His-tagging has been a monumental breakthrough in isolating recombinant proteins. Since the labeling process for imaging has been arduous and limiting, we've created a simple reagent that labels almost any His-tagged recombinant protein for imaging - even under the electron microscope - in just one step. --James F. Hainfeld, PhD Nanoprobes founder and chief mad scientist. See His-tagged proteins directly under EM --no silver or gold development required--

Nanoprobes was founded to develop the most sensitive reagents and technology for detecting biological molecules, and we're doing just that.

Our unique gold labeling technology uses chemically cross-linked metal clusters and nanoparticles as labels.

Unlike conventional immunogold probes, in which colloidal gold particles are electrostatically adsorbed to antibodies and proteins, our gold labels are uncharged molecules which are cross-linked to specific sites on biomolecules. This gives our probes greater range and versatility than colloidal gold.

Our labels can be attached to any molecule with a reactive group -- proteins, peptides, oligonucleotides, small molecules and lipids -- for detection and localization. Other labels can be combined with our gold labels; our unique FluoroNanogold probes combine Nanogold® and fluorescein into a single probe for imaging a specimen both by fluorescence and electron microscopy.

New probes can be engineered based on any fragment of a naturally occurring biomolecule, and the label can be positioned away from the binding site so it does not interfere with binding.

Our Nanogold® probes have been cited in over 250 publications, and are used in the laboratories of several Nobel Laureates. It's all about creating better tools and finding innovative solutions, so that research and treatments can move ahead.

Drop us a line and let us know what you're working on. We'll be glad to help.