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Golden Lipids


Product Catalog

Nanogold® Labeling Reagents
Recombinant Protein Detection

 

Ni-NTA-Nanogold®New
GoldiBlot™
Nanogold® Conjugates
AuroVist™New
FluoroNanogold™
Gold Lipids
Silver Enhancement
GoldEnhance
EnzMet™
Negative Staining
Conducting Polymers
Undecagold
Custom Synthesis
Colloidal Gold

Order Form (for Purchase Orders)
Current Price List (pdf)
Ordering Information

Contents

 

Introduction

Gold lipids are another unique product from Nanoprobes. Each lipid molecule is covalently linked to a Nanogold® or undecagold cluster through its polar head group. Since the gold moiety is hydrophilic, these molecules retain the amphiphilic nature of the parent lipid, and behave like fatty acids or phopholipids.

They may be used to study membranes by incorporation into the lipid phase, or they may be used to gold-label micelles and vesicles so that they can be identified and visualized.

The gold labels may be visualized directly by EM. Using silver enhancement, they may be seen in the light microscope, or by eye in lipoimmunoassays and similar applications.


Buy nowFeatures

  • Discrete single molecules with one lipid to one gold cluster label.
  • Covalent attachment ensures consistent structure and properties.
  • Stable, long shelf life.
  • Soluble in organic solvents and alcohols for easy incorporation into liposomes.

Diagram of Palmitoyl Gold and DPPE-Gold (12k)


Buy nowApplications

  • Follow liposomal transport or drug delivery by EM or LM (see: Adler-Moore, J.: Bone Marrow Transplantation, 14, S3-S7 (1994)):

    Diagram: tracking gold-labeled micelles by microscopy (27k)

    Schematic showing the pathways of Nanogold®-labeled liposomes in cells, as revealed by EM. Ambisome is a channel-forming anti-fungal drug: in its absence, the pattern of the label as revealed by silver enhancement shows that the liposome fuses with the cell membrane (left), but when it is present, the liposomes enter the cell (right) and Nanogold® accummulates in the cytoplasm (Adler-Moore, J.; Bone Marrow Transplantation, 14, S3-S7 (1994)).

  • Prepare novel arrays and nanostructures using the phase properties of labeled liposomes. See:

    • Hainfeld, J. F.: Proc 54th Ann. Mtg. Micros. Soc. Amer., San Francisco Press, San Francisco, CA, pp. 898-899 (1996).

    • Hainfeld, J. F.; Furuya, F. R., and Powell, R. D.: Metallosomes. J. Struct. Biol., 127, 152-160 (1999).

  • Silver-enhanced gold generates a highly visible, permanent signal in lipoimmunoassays.

Buy nowReferences


Information - Nanogold® Lipids

4020 Palmitoyl Nanogold® 4021 DPPE Nanogold®
Instructions and Product information (html) Instructions and product information (html)
[4020-PDF]  Product information (PDF) [4021-PDF]  Product information (PDF)
[4020-PDF]  Material Safety Data Sheet (PDF) [4021-PDF]  Material Safety Data Sheet (PDF)

Information - Undecagold Lipids

4022 Palmitoyl Undecagold 4023 DPPE Undecagold
Instructions and Product information (html) Instructions and product information (html)
[4022-PDF]  Product information (PDF) [4023-PDF]  Product information (PDF)
[4022-PDF]  Material Safety Data Sheet (PDF) [4023-PDF]  Material Safety Data Sheet (PDF)




Price List:
Gold Lipids
Custom labeling is also available for other lipids and related molecules.
Paying by Purchase Order? Please use our Online Order Form.
#4020 Palmitoyl Nanogold® The C15 palmitic acid (a fatty acid) covalently attached to the 1.4 nm Nanogold® particle. 30 nmol
$331
Qty:
#4021 DPPE Nanogold® Dipalmitoyl phosphatidylethanolamine covalently attached to the 1.4 nm Nanogold® particle. 30 nmol
$364
Qty:
#4022 Palmitoyl Undecagold The C15 palmitic acid (a fatty acid) covalently attached to the 0.8 nm Nanogold® particle. 30 nmol
$288
Qty:
#4023 DPPE Undecagold Dipalmitoyl phosphatidylethanolamine covalently attached to the 0.8 nm undecagold particle. 30 nmol
$314
Qty:
Australia and Singapore: Please order through our distributor.
International orders: Our local distributors can provide expedited customs processing and delivery to your area.
Paying by purchase order? Please use our online order form.

 


Custom Labeling

Custom labeling may be available for some other lipids or related molecules: check out our suggestions for ordering.
Use our Online Custom Synthesis Form, call or email us at tech@nanoprobes.com for a quote.

 

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